Genetic control of natural resistance to infection and malignancy by International Symposium on the Genetic Control of Natural Resistance to Infection and Malignancy (1980 MontreМЃal, QueМЃbec)

Cover of: Genetic control of natural resistance to infection and malignancy | International Symposium on the Genetic Control of Natural Resistance to Infection and Malignancy (1980 MontreМЃal, QueМЃbec)

Published by Academic Press in New York, N.Y .

Written in English

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Subjects:

  • Natural immunity -- Congresses.,
  • Infection -- Immunological aspects -- Congresses.,
  • Cancer -- Immunological aspects -- Congresses.,
  • Immunogenetics -- Congresses.,
  • Immunity, Natural -- Congresses.,
  • Immunogenetics -- Congresses.,
  • Infection -- Immunology -- Congresses.,
  • Neoplasms -- Immunology -- Congresses.

Edition Notes

Includes bibliographies and index.

Book details

Statementedited by Emil Skamene, Patricia A.L. Kongshavn, Maurice Landy.
SeriesPerspectives in immunology
ContributionsSkamene, Emil., Kongshavn, Patricia A. L., Landy, Maurice.
Classifications
LC ClassificationsQR185.2 .I57 1980
The Physical Object
Paginationxxi, 598 p. :
Number of Pages598
ID Numbers
Open LibraryOL4107925M
ISBN 100126476802
LC Control Number80022733

Download Genetic control of natural resistance to infection and malignancy

Genetic Control of Natural Resistance to Infection and Malignancy is a collection of papers presented at the Proceedings of an International Symposium of the Canadian Society for Immunology held in Montreal, Quebec.

It provides information about the different models of genetic resistance to various diseases. Miscellaneous: Genetic control of natural resistance to infection and malignancy.

pp ref.9 Abstract: The genetic control of resistance to Rickettsia tsutsugamushi infection was analysed based on the responses to infection of the F 1 s, F 2 s and backcrosses from matings of BALB/c (resistant) and C3H/He (susceptible) mice mice Cited by: 7.

Cheers C, McKenzie IFC, Mandel TE, Chan YY () A single gene (Lr) controlling natural resistance to murine listeriosis. In: Genetic control of natural resistance to infection and malignancy. Academic, New York Google ScholarCited by: Some of the earliest studies of genetic differences in pathogenesis of S.

pneumoniae infections were done with the BS and BR mice which were bred by Lesslie Webster to be susceptible or resistant to infection with Salmonella enteritidis (Webster ).Cited by: Genetics and Breeding for Disease Resistance of Livestock is a solid resource that combines important information on the underlying genetic causes and governing factors for disease resistance in food animals and applications for breeding purposes.

It describes genomics at each species level to help researchers and students understand disease. Natural resistance of mice to infections with Salmonella typhimurium and Leishmania donovani is regulated by chromosome 1 gene(s) designated Ity Cited by:   Genetic factors play a key role in host response, disease severity, and ultimate outcome of infection with Mycobacterium tuberculosis in humans.

In Cited by: Among the genetic factors, the CCR5-delta 32 (CCR5-∆32) mutation has been the most widely investigated and is associated with natural resistance to HIV infection, because it efficiently inhibits entry of R5 strains; some treatments against HIV infection Cited by: Publisher Summary. Natural resistance to infection with several intracellular pathogens— both bacterial and protozoal—has recently been demonstrated to be under genetic control.

The ability of genetically-resistant mouse strains to prevent growth, in the reticuloendothelial tissues, of Mycobacterium bovis (BCG) is controlled by a single, Genetic control of natural resistance to infection and malignancy book, Cited by: 3.

Natural resistance to M. tuberculosis infection. Genetic control of resistance to Tuberculosis infection in mice and humans. The ‘golden age’: why does the frequency of Tuberculosis decrease in children between age 5 and adolescence.

Tuberculosis resistance in long-term sensitized persons. Innate cellular resistance to. Genetic control of natural resistance to Leishmania donovani Affiliations. Sir William Dunn School of Pathology, South Parks Road, Oxford, OX1 3RE, UKCited by: Natural resistance is now coming to be recognized as a potentially important phenomenon in host defense against infection and ma­ lignancy.

Genetically controlled resistance mechanisms are usUally effective early in infection and before conventional immune responses are generated. Genetic control of natural resistance to infection and malignancy.

New York, N.Y.: Academic Press, (OCoLC) Online version: International Symposium on the Genetic Control of Natural Resistance to Infection and Malignancy ( Montréal, Québec). Genetic control of natural resistance to infection and malignancy. One of the fundamental observations made by Bang and co-workers some thirty years ago was that MHV infection of the host proceeds in a series of stages, which can be seen as three sequential barriers of host resistance 1–3.

These stages have also become the key to dissecting the genetic control of host resistance to by: 1. International Symposium on the Genetic Control of Natural Resistance to Infection and Malignancy ( Montréal, Québec).

Genetic control of natural resistance to infection and malignancy. New York, N.Y.: Academic Press, (DLC) (OCoLC) Material Type: Conference publication, Document, Internet resource: Document Type.

Discover the best Drug Resistance books and audiobooks. Learn from Drug Resistance experts like Elsevier Books Reference and Elsevier Books Reference. Read Drug Resistance books like Genetic Control of Natural Resistance to Infection and Malignancy and Drug Resistance As a Biochemical Target in Cancer Chemotherapy for free with a free day trial.

The exact mechanisms involved m the resistance phenotype are not known, but include enhanced recruitment of mononuclear phagocytes at the infectious loci, a process that may be regulated by the C5 protein Genetic control of resistance to another impommt human disease, malaria, has been revealed using mouse by:   Genetic control of Leishmania populations within the host.

Genetic control of acute susceptibility of mice to L. donovani infection. Clin Exp Immunol ; – CASCited by: Get this from a library.

Genetic Control of Natural Resistance to Infection and Malignancy. [Emil Skamene] -- Genetic Control of Natural Resistance to Infection and Malignancy.

Despite traditional disease control measures, losses attributable to infectious diseases continue to impede the livestock industries.

An alternative approach to this problem is genetic disease resistance involving both immune and non-immune mechanisms, which is the inherent capacity of a previously. "The Symposium on Genetic Control of Natural Resistance to Infection and Malignancy, which formed the basis of this volume, was held under the auspices of the Montreal General Hospital Research Institute."--P.

xxi. EXPERIMENTAL PARAS1TOL () Trypanosoma congolense: Genetic Control of Resistance to Infection in Mice MARGARET PINDER Centre de Recherches sur les Trypanosomoses Animales (CRTA), B.P.Bobo-Dioulasso, Republic of Upper-Volta, West Africa (Accepted for publication 5 December ) PINDER, M.

Cited by: Genetic control of host resistance to infection and malignancy. New York: Liss, © (OCoLC) Online version: Genetic control of host resistance to infection and malignancy.

New York: Liss, © (OCoLC) Material Type: Conference publication: Document Type: Book: All Authors / Contributors: Emil Skamene. Goto Y, Nakamura RM, Takahashi H, Tokunaga T () Genetic control of resistance to Mycobacterium intracellulare infection in mice.

Infect Immun –, Google Scholar Gray DF () Variations in natural resistance to by: Genetic control of systemic Leishmania major infections: dissociation of intrahepatic amastigote replication from control by the Lsh by:   The successful infection of human GII.4 virus in stem cell-derived intestinal enteroids has recently shown that commensal bacteria is not required for infection and that enteroids from non-secretors are resistant to GII.4 infections, altogether further supporting that secretor status is a strong restriction factor for GII.4 virus by:   Salmonellosis is a frequent disease in poultry stocks, caused by several serotypes of the bacterial species Salmonella enterica and sometimes transmitted to humans through the consumption of contaminated meat or eggs.

Symptom-free carriers of the bacteria contribute greatly to the propagation of the disease in poultry stocks.

So far, several candidate genes and quantitative trait loci (QTL Cited by: Genetic Control of the Susceptibility to Bacterial Infection It seems that you're in USA. We have a dedicated site for USA Genetic Control of the Susceptibility to Infection with Pathogenic Bacteria.

Pages Genetic Control of Resistance to Mycobacterial Infection. Interactions amongst genes, known as epistasis, are assumed to make a substantial contribution to the genetic variation in infectious disease susceptibility, but this claim is controversial.

Here, we focus on the debate surrounding the evolutionary importance of interactions between resistance loci and argue that its role in explaining overall variance in disease outcomes may have Cited by:   Despite much research on immunological responses to helminth parasites, knowledge of the dynamic interplay between levels of herd immunity in humans and the rates of exposure, establishment and Cited by: A major physiological determinant of snail resistance/susceptibility to infections, which is also under genetic influence, is the snail internal defense system (IDS).

The IDS comprises the cellular elements (hemocytes) and the humoral (plasma) factors of the hemolymph that work independently or in concert to recognize, encapsulate, kill, and clear intruding trematodes [ 6, 54, 55, 56 ].Cited by: 4.

Inbred mouse strains differ in their resistance to infection with the human pathogen Trypanosoma rhodesiense. Of the strains tested, C57BL/6 (B6) mice were the most resistant, and BALB/c (C) mice. ISBN: OCLC Number: Description: xi, pages: illustrations ; 25 cm.

Contents: Genetic control of the susceptibility to infection with pathogenic bacteria / J.B. Zabriskie and A. Gibofsky --Genetic approaches to the study of disease resistance / D.E. Briles [and others] --Influence of host genes on resistance of inbred mice.

Perhaps the most well known resistance is that which is provided by sickle-cell anemia to malaria. Malaria is one of the leading causes of death in the global human population, with million people infected and two million people dying of it per year [10].Sickle-cell anemia is a genetic condition that results in misshapen red blood cells, and the crescent-shape helps prevent the malaria.

v ol. 69, genetic resistance in s. pneumoniae infection median survival times were seen (Fig. 1), correlating with the number of pneumococci in the blood 24 h postinfection (Fig. News update, July The risk posed by using antibiotics in livestock is a global one, according to recent news.

In May, researchers announced the first case of a patient in the United States infected with bacteria resistant to a so-called "treatment of last resort" — an antibiotic reserved for certain, unusually dangerous infections.

Misuse of antibiotics, such as prescribing them for non-bacterial infections (colds, influenza, most upper respiratory infections, etc.) or prescribing the "newest" antibiotic on the market when older brands may still be as effective simply inceases the rate at which this natural selection for resistance occurs.

A review is given of genetically determined mammalian resistance to protozoan infections with particular reference to Plasmodium sp. (of West Africans to P. vivax and of different strains of mice to rodent malaria), to Toxoplasma gondii in mice, to Entamoeba histolytica and to trypanosomes (especially in N'dama cattle).

A longer account is provided of genetic resistance of mice to Leishmania by: Schistosomiasis remains the most important tropical snail-borne trematodiasis that threatens many millions of human lives.

In achieving schistosomiasis elimination targets, sustainable control of the snail vectors represents a logical approach. Nonetheless, the ineffectiveness of the present snail control interventions emphasizes the need to develop new complementary strategies to ensure more Cited by: 4.

Human genetic resistance to malaria refers to inherited changes in the DNA of humans which increase resistance to malaria and result in increased survival of individuals with those genetic changes.

The existence of these genotypes is likely due to evolutionary pressure exerted by parasites of the genus Plasmodium which cause malaria. Since malaria infects red blood cells, these genetic changes. The concept that susceptibility and resistance to infectious diseases is genetically determined has been established for more than 20 years, and genetic regulation of host responsiveness to C.

albicans infection is neither novel nor unexpected. Nevertheless, many published models of the disease have failed adequately to consider the effect of Cited by:   Abstract. The natural resistance–associated macrophage protein 1 (NRAMP1) is implicated in the pathophysiology of mycobacterial infections.

We investigated by polymerase chain reaction previously published Nramp1 genotypes at 4 loci—INT4, ND, 3′UTR, and 5′(CA) n microsatellite markers—in human immunodeficiency virus–negative patients with tuberculosis and healthy control Cited by:   Foliar fungal pathogens from the genus Mycosphaerella affect eucalypts in natural forests and plantations worldwide.

QTL analysis was conducted to dissect the genetic control of resistance in Eucalyptus globulus to a natural infection by Mycosphaerella leaf disease, using a clonally replicated outbred F2 family ( genotypes) planted in a field trial.

Two major QTL, with high LOD support (20 Cited by:

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